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  By Michael Holden, Kate Holton and Alistair Smout
  
  LONDON, Sept 14 (Reuters) - King Charles, his sons Princes William and Harry and other senior royals joined a solemn procession taking Queen Elizabeth's coffin as the late monarch made her final journey from Buckingham Palace
  on Wednesday.
  
  Huge crowds gathered in central London to witness the queen being taken from the palace to parliament as artillery guns fired salutes and Big Ben tolled, the latest in a series of poignant ceremonies
  website as the nation mourns the queen website who died last week aged 96
  after seven decades on the throne.
  
  Lying on a gun carriage, covered by the Royal Standard flag and with the Imperial State Crown placed
  on a cushion on top alongside a wreath of flowers,
  the coffin bearing Elizabeth's body was taken in a slow,
  somber procession from her London home to Westminster Hall.
  
  
  There it will lie in state for four days.
  
  Walking directly behind were Charles website and his siblings, Anne, Andrew and Edward.
  
  
  
  In a group that followed were Charles's sons Princes William and Harry, a doleful scene reminiscent of when, as boys 25 years ago, they followed the casket of
  their mother Princess Diana when it was taken on a similar procession through central London.
  
  It was also a symbolic show of unity website as William, 40,
  now the Prince of Wales, and Harry, 37, the Duke of Sussex, are said to be barely be
  on speaking terms after a bitter falling
  out in the last couple of years.
  
  "It was very moving, seeing the family. It was a powerful show of unity," said Jenny Frame, 54, who waited for
  more than four hours to see the procession.
  
  Paul Wiltshire, 65, commented: "I don't think we'll see anything like that again ever, or a queen like that again. An end of an era."
  
  HUSHED SILENCE
  
  A military band playing funeral marches and soldiers in ceremonial scarlet uniforms, some with shiny silver breastplates and helmets, accompanied the
  gun carriage pulled by the King's Troop, Royal Horse Artillery, as it moved slowly through central
  London, where many roads were closed to traffic.
  
  
  Guns fired every minute at Hyde Park, while parliament's famous Big Ben bell also rang at 60-second
  intervals.
  
  The crowds stood in a hushed silence as they watched the procession but
  then broke into spontaneous applause when it passed.
  Some threw flowers.
  
  Other senior royals including Charles' wife Camilla website now the Queen Consort, Kate, William's wife and now Princess of Wales,
  and Harry's wife, Meghan, traveled by car.
  
  When the procession reached Westminster Hall, a medieval
  building with origins dating back to 1097 and the oldest part of the Palace
  of Westminster that houses the British parliament, the coffin was carried
  inside by soldiers from the Grenadier Guards and placed on a catafalque surrounded by candles.
  
  
  A short service followed, conducted by the Archbishop of Canterbury, the spiritual head of the Anglican Church,
  as senior politicians watched on. The royals quietly departed, with
  Harry and Meghan holding hands.
  
  A constant vigil will be held by soldiers in full ceremonial uniforms
  at the four corners of the catafalque.
  
  Just after 5 p.m.
  
  the public began to file past the coffin, some in tears, many
  bowing their heads. There will be a constant stream of
  mourners, 24-hours a day, during the four days of lying in state that lasts until the morning of the funeral website on Sept.
  19.
  
  "We've lost someone special," said Kenneth Taylor, 72, who
  stayed overnight in a tent to be one of the first in the
  queue.
  
  He said a lump had come to his throat as he viewed the
  queen lying in state. "Her service to this country was really steadfast and unswerving."
  
  A Buckingham Palace spokesperson said Elizabeth had three
  keys roles in her life: head of the family, head of the nation and
  head of state.
  Wednesday marked the moment the coffin passed from the family
  to the state.
  
  LONG QUEUE
  
  People started waiting in line website late on Tuesday, sleeping on the street in the rain,
  to be one of the first to file past the coffin, and there
  was already a queue over 2 miles long.
  
  Among those gathered, some were there to represent elderly parents, others to witness history
  and many to thank a woman who, having ascended the throne
  in 1952, was still holding official government meetings just two days before she died.
  
  
  The government has warned the queue could eventually stretch for up to 10 miles (16
  kilometers) along the southern bank of the River Thames, winding past landmarks such as the giant London Eye ferris wheel and a reconstruction of Shakespeare's Globe
  theater.
  
  Culture Secretary Michelle Donelan said some people might have to stand in line for as long as 30 hours in order to file past the coffin before Monday's
  funeral.
  
  "She's an icon of icons," mourner Chris Imafidon said.
  
  "I must at least endure this camping out of respect."
  
  Speaking to people in the queue, the Archbishop of York Stephen Cottrell, quipped: "We are honoring two great British traditions, loving the queen and loving a queue."
  
  Elizabeth's coffin was flown back London late on Tuesday from Scotland, where
  it had been since her death at her Scottish summer holiday home Balmoral
  Castle, with tens of thousands of people lined the
  14-mile (22 km) route in driving rain.
  
  In Scotland, about 33,000 people filed past the coffin during the 24 hours it was at St Giles' Cathedral in Edinburgh, but the memorial in London is a much larger occasion.
  
  As many as 750,000 mourners are expected to
  walk through Westminster Hall to pay their final respects.
  
  
  A senior palace official described Wednesday's poignant pageant as relatively small and personal.
  
  
  The full-scale ceremonial procession on the day
  of her funeral is likely to be one of the biggest the country
  has ever witnessed.
  
  Royalty, presidents and other world leaders are expected to attend, although no one from certain nations, such as Russia, Afghanistan, and Syria will be invited.
  
  
  U.S.
  
  President Joe Biden, who has said he would be there, spoke to the new king earlier on Wednesday, the White House said,
  and "conveyed the great admiration of the American people for the queen."
  
  (Additional reporting by Farouq Suleiman, William James, Elizabeth Piper, Muvija M, Sachin Ravikumar, Humza Jilani,
  Aiden Nulty and Manuel Ausloos; Editing by Janet Lawrence, Alex Richardson, Alexandra
  Hudson)
  
  
  
  
  
  Sagae Japan (http://www.london.umb.edu)

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  دیابت
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  تجویز گاباپنتین به‌عنوان پیش‌دارو، یک روش موثر برای کنترل پاسخ‌های همودینامیک به لارنگوسکوپی و لوله‌گذاری می‌باشد.
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  قبل از مشورت با پزشک، مصرف گاباپنتین را برای کنترل تشنج شروع یا قطع نکنید.

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